The common error "Profile is missing" indicates that the Umbrella module is installed but the profile (OrgInfo.json) is not. This means the Umbrella module cannot register with Umbrella or enable protection.
To resolve this for an existing installation simply add the profile here:
%ProgramData%\Cisco\Cisco AnyConnect Secure Mobility Client\Umbrella\OrgInfo.json
Use the orginfo.json from your computer and paste this into the location above
To correct the error for future installations, ensure this profile is properly embedded within the deployment package:
\Profiles\umbrella\OrgInfo.json